NEW Biology Discovered

Inflammation is your body's defense against injury and infection. Common signs of inflammation are pain, heat, redness, swelling, and loss of function. Inflammation can either happen in the short term (acute) or be a long-term response (chronic). The 3 major cell types involved in chronic inflammation are T cells, B cells and monocytes.

Monocytes are a type of immune cells that form in the bone marrow and participate in both innate and adaptive immune responses. Monocytes travel through the blood to inflamed tissues and are key players in driving and perpetuating the chronic stage in inflammatory diseases.

Monocytes are key drivers of the inflammatory process and maintain the chronic stage in various inflamatory diseases.

Our program is based on the discovery of a novel adhesion checkpoint protein that is selectively expressed on the surface of monocytes and controls their ability to migrate (or 'walk' to) towards inflamed tissues. This protein is called MOSPD2 (the "mono-walk" receptor).