NEW BIOLOGY DISCOVERED

Inflammation is your body's defense against injury and infection. Common signs of inflammation are pain, heat, redness, swelling, and loss of function. Inflammation can either happen in the short term (acute) or be a long-term response (chronic). Key cell types involved in chronic inflammation are lymphocytes (T- and B- cells), monocytes and neutrophils.

Myeloid cells are a group of immune cells that form in the bone marrow and travel through the blood to inflamed tissues, where they participate in both innate and adaptive immune responses. Myeloid cells such as monocytes and neutrophils are key players in chronic inflammatory diseases.

Our program is based on the discovery of a novel adhesion checkpoint protein called MOSPD2, which is selectively expressed on the surface of monocytes and neutrophils and controls their ability to enter inflamed tissues.