POINTGUARD is a randomized, blinded, placebo-controlled dose-ranging study evaluating the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of subcutaneous single and multiple ascending doses of IW-601.
In December 2025, ImmuneWalk announce that the POINGUARD Phase 1 clinical trial met all primary and secondary endpoints and demonstrated positive safety, pharmacokinetics and mechanistic validation.
Phase 1b/2a Study in Behçet's Disease, an orphan inflammatory indication selected for initial proof-of-concept, is planned to start in Q2 2026, followed by Phase 2b Study in highly prevalent I&I disease in 1H 2027.
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